Results of clinical studies :

Use test carried out over 28 days:

3% Matrikines peptides

Peptides are proteins made up of amino acids which our body uses to repair, protect or regenerate cells. If the skin's elastin or collagen is damaged, Peptides, like all-important messengers, will tell the skin tissue to produce more of them. A young metabolic system naturally produces these peptides at the right moment; but with time and environmental oxidation, these chemical messengers slow down their activity, and the body struggles to regenerate itself. For fill wrinkles and provide a lifting effect we have chosen biomimetic Matrikine Peptides (as they mimic the repair mechanisms of native cells). At a dosage of 3%, they stimulate the synthesis of extracellular matrix macro-molecules (Collagen, Fibronectin, Hyaluronic Acid, etc.), fill in wrinkles and restructure the skin's mesh for renewed firmness.

2% Encapsulated and stabilized vitamin C

Vit C is a very powerful antioxidant, with anti-wrinkle and anti-wrinkle and brightening properties. Unfortunately, it degrades at the slightest contact with light and air, and becomes inactive. We have therefore chosen an encapsulated Vitamin C which, although highly technical and difficult to produce (hence its rarity), will be stabilized, i.e. protected from air and light to enable it to retain its full efficacy. Its gradual release into the skin's deeper layers not only improves tolerance, but also considerably amplifies its results compared with conventional Vitamin C.

5% Niacinamide Grade S

We have chosen a pure, powdered Grade S Niacinamide for maximum concentration and tolerance for sensitive skin. Grade S ensures a Niacinamide concentrated in Nicotinamide, the active part of the molecule. It contains no Nicotinic Acid, which is the irritant in conventional Niacinamides. 

As well as being extremely well-tolerated, the results on the skin are remarkable: collagen and elastin are boosted for firmer skin, while melanin transfer is reduced to minimize the appearance of pigmentation spots.

1% Encapsulated Retinol

We chose to use Encapsulated Retinol because of its many technical advantages:

In the dermis, this encapsulated Retinol stimulates Hyaluronic Acid synthesis and strengthens fibroblasts to promote collagen and elastin production, improving skin elasticity.

In addition, Retinol improves epidermal proliferation and differentiation, effectively reducing pigmentation spots and wrinkles.

1% Non-cross-linked high molecular weight hyaluronic acid

We have chosen a pure, powdered (=maximum concentration), non-cross-linked, high-molecular-weight Hyaluronic Acid. Why non-crosslinked? Because its molecules are not linked to each other, and are therefore free to distribute themselves evenly throughout the epidermis. Its molecular weight of 1000 Kda binds water (up to 1000 times its weight in water) for an immediate plumping effect, while reinforcing the cutaneous barrier and limiting water loss.. 

Results: a significant reduction in the appearance of fine lines and wrinkles, smooth, plump skin.

1% Dioic acid

We use pure Dioic Acid powder to ensure maximum concentration, without preservatives. It is obtained by biofermentation of natural oleic acid, reinforcing its quality. This Dioic Acid has a powerful anti-spot effect by inhibiting tyrosinase responsible for melanin production. It regulates cell renewal promoting the elimination of pigmented cells and diminishing existing spots. Its antioxidant properties neutralize free radicals, reducing skin damage and blemishes. It also has an anti-inflammatory action to soothe inflammatory skin responses linked to pigmentation.

Advice from Dr Nicolas B.

Mesotherapy, also known as poly-vitamin injections, is an effective, fast-acting aesthetic medicine treatment that involves injecting non-crosslinked hyaluronic acid, vitamins and essential active ingredients into the skin to boost elasticity, improve hydration and even out skin tone. I drew inspiration from mesotherapy sessions to formulate this Serum Intense Nuit: Peptides matrikines, encapsulated Vitamin C, encapsulated Retinol, non-cross-linked Hyaluronic Acid, Niacinamide Grade S, Dïoic Acid ... all powerful ingredients, and highly dosed to continue evening out the complexion and stimulate skin firmness at home. And if I've chosen a Night application, it's to capitalize on this period of intense cellular activity and revitalize your skin in depth. After applying this Intense Night Serum, apply the Intense Night Cream to accelerate the penetration of active ingredients and double the doses of Niacinamide Grade S, Encapsulated Retinol, Hyaluronic and Dioic Acids...the results will be even more striking!

MAKE YOUR PERSONALIZED DIAGNOSIS

Take a small amount of product equivalent to the length of your first distal phalanx (the one with your nail). Emulsify the product between your hands before applying it all over the face, pressing with your palms from the inside out. Reapply to emphasize the neck and décolleté areas.